Current Issue : April - June Volume : 2019 Issue Number : 2 Articles : 6 Articles
Background. Antibacterial clothes are classified as a complementary treatment in line with antisepsis, although meta-studies are\nunable to find significant improvements of eczemas. Methods. The antibacterial effectiveness of conventional AD clothes was\ncompared across each other by (i) standard suspension tests for the appraisal of antibacterial products and (ii) a real-life setup of\naffected ADskin using S. aureus colonised artificial skin, to assess if functional clothes are effective under practicalwear conditions.\nAdditionally, the interaction of the fibre types with a moisturising cream was evaluated during a real wearing situation and after\ndomestic laundry. Results. In the real-life setup simulating dry skin microenvironment, all samples failed to reduce S. aureus. Silver\nand zinc-fabrics showed a slight activity only under unrealistic moist conditions. When using standard suspension tests, samples\ndiffered considerably in their antibacterial effectiveness, where silver and zinc endowed fibres outperformed AEGIS endowed\nsilk fabrics. Garments absorbed the cream dependent on the particular fibre types. Furthermore, domestic laundry was unable\nto completely remove the cream. Conclusion. Considerable differences in the antibacterial effectiveness of conventional AD clothes\nwere revealed. Under practical (dry) wear conditions, garments were unable to modify skin colonization with S. aureus, although\neffectiveness can be triggered by wetting the garments. Remnants of moisturising cream remain on the fibres after laundry....
We examined the changes in numerous skin conditions before and after the application of\ninterferential current therapy to various regions of healthy male bodies. In this study, we\nassessed the differences in the skinâ??s sebum, moisture levels, pores, wrinkles, pigmentation,\nand elasticity on the shoulders, lower back, and the knees of Korean males in their 20s. A\ntotal of 30 healthy males were included in the study. We used a skin diagnosis meter as a\ndevice for measuring the state of the skin. A statistical difference was found when comparing\nthe pre- and post-measurement values in regards to the moisture levels, wrinkles, and\npigmentation. In the correlation analysis results, the sebum and pigmentation, moisture levels\nand wrinkles, moisture levels and pigmentation, and moisture levels and elasticity were\nall positively correlated, respectively. The results of this study partially suggest that a change\nin skin condition is associated with external stimulation. The study also found that the effects\nof the application of interferential current therapy on the various skin conditions may\ndiffer depending on the region of the body that the application is conducted as well....
The aim of our study was to recognize different skin conditions of the face\nand neck using six biophysical parameters and to show the changes after the\napplication of ultrasonic stimulation (US). We assessed the differences in the\nsebum, moisture, pores, wrinkles, pigmentation, and elasticity of the skin in\nthe face and neck regions. A total of 30 healthy men in their 20s were\nenrolled. We used a skin diagnosis meter to assess the state of the skin. The\nsebum and pores of the face were more significant than in the neck. The\namount of moisture in the U-zone was significantly higher than in other\nareas. Statistical differences were found between the pre- and post-measurement\nvalues in the sebum, moisture, wrinkles and pigmentation. Wrinkles\nand pigmentation were positively correlated. Our data showed that the\nchanges in skin condition are associated with external stimulants. The effect\nof US on skin may differ depending on the part of the body, and some biophysical\nproperties of skin vary depending on the location on the body....
IL-27 has been shown to have both tumor promoting and suppressing functions. IL-27, with its diverse influences on immune\nresponses, has not been studied extensively in nonmelanoma skin cancers (NMSC), including Squamous and BasalCellCarcinomas\n(SCC and BCC), and its roles in tumor initiation, progression, and its probable use in NMSC treatment have yet to be unveiled. A\ncross-sectional analytical study was designed to investigate the serum levels of IL-27 in NMSC patients in comparison to normal\nindividuals. Levels of IL-27 in the sera of 60 NMSC patients along with 28 healthy controls weremeasured bymeans of quantitative\nenzyme-linked immunosorbent assay (ELISA). In this study we observed that IL-27 serumlevelswere significantly higher inNMSC\npatients in comparison to healthy individuals (0.0134 versus 0.0008 ng/ml; P<0.001). Furthermore, when subcategorized based on\npathological diagnosis, both BCC and SCC patients had higher levels of IL-27 in their sera compared to controls (P=0.002 and\nP=0.033; respectively). However, these levels were not different among SCC and BCC patients. According to our results, it seems\nthat IL-27 is involved in antitumor immune responses in NMSCs. On the other hand, these observationsmight be indicative of this\ncytokine involvement inNMSCtumorigenesis and progression.Therefore, administration of this cytokine for therapeutic purposes\nin patients with such conditions should be erred on the side of caution....
Objective.Melasma is a highly prevalent, chronic, and pigmentary disorder.This systematic review aims to evaluate the efficacy and\nsafety of tranexamic acid (TA) for the treatment of adults with melasma. Methods. We independently searched 3 databases from\nbeginning to 26 April, 2018. The study included 21 eligible trials. Two writers extracted data at the same time independently. Study\noutcomes were calculated by standardized mean differences (SMD) with 95% confidence intervals (CIs). All statistical analyses\nwere performed using Review Manager Version 5.3 and STATA Version 15.1. Results.The combined results showed that the use of\nTA was associated with reduced Melasma Area and Severity Index (MASI) and Melanin Index (MI). No significant difference in\nErythema Index (EI) was observed with TA treatment. Side effects were minor, with a few cases reporting mild gastrointestinal\nreaction, oligomenorrhoea, hypopigmentation, urticarial rash, and skin irritation xerosis. Conclusion.Themeta-analysis suggested\nthat TA treatment appeared to be a promising therapeutic approach for melasma....
In the treatment of extensive burns, cultured epithelial autograph (CEA) became\navailable commercially in Japan from 2009. Based on the 6 years multicenter\nsurveillance data on using CEA for extensive burns, it is reported that\nusing 6:1 split thickness skin graft together with CEA is successful after\nwound bed preparation for extensive deep dermal burn or patients with deep\nburn...
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